Signs of adulthood type 2 diabetes 'visible in eight year olds'
Warning signs of adulthood type 2 diabetes can be spotted in children as young as eight, research suggests. Scientists from the University of Bristol looked at blood samples from over 4,000 people aged eight, 16, 18 or 25.
Higher levels of “bad” cholesterol and inflammation were linked to the youngsters developing type 2 diabetes in later life. The scientists hope better understanding how the disease unfolds will help doctors intervene earlier.
Read more: Diabetes: everything you need to know
Around 3.9 million people in the UK were living with a diabetes diagnosis in 2019, of whom 90% had type 2. Type 1 diabetes comes about when the immune system mistakenly attacks the cells that produce the blood-sugar lowering hormone insulin.
In type 2 diabetes, the body does not produce enough insulin or does not respond to the hormone that is made.
Unlike type 1, type 2 diabetes is often associated with being overweight or inactive. Type 2 is also linked to having a family history of the condition. To better understand how it develops, the Bristol scientists followed participants of the Children of the ‘90s health study.
Most of the youngsters did not have type 2 diabetes or any other chronic disease at the time.
Genetic information was combined with metabolomics, measuring small molecules in blood to identify patterns specific to the early stages of type 2 diabetes.
Read more: Type 2 diabetics '50% more likely to die prematurely'
Results, published in the journal Diabetes Care, flagged several warning signs. Certain types of “good” cholesterol were reduced in the eight year olds who went on to become diabetic, while “bad” forms were raised.
Inflammation and some amino acids, the building blocks of proteins, were also elevated by ages 16 and 18.
These differences became more pronounced as the participants grew older. a hand holding a yellow neck tie: obese woman measuring her waist with a measuring tape against a white background© Provided by Yahoo! Style UK obese woman measuring her waist with a measuring tape against a white background.
“We knew diabetes doesn't develop overnight”, said lead author Dr Joshua Bell. “What we didn't know is how early in life the first signs of disease activity become visible and what these early signs look like. “Diabetes is most common in older age, but we see signs of disease susceptibility very early on; about 50 years before it's usually diagnosed.
“Knowing what these early signs look like widens our window of opportunity to intervene much earlier and stop diabetes before it becomes harmful.” Read more: Two cups of filtered coffee a day ‘slashes the risk of type 2 diabetes’
The scientists stressed the participants were largely not diabetic at the time of the study, but showed warning signs.
“We're talking about the effects of susceptibility rather than of clinical disease itself,” said Dr Bell. “This does not mean young people ‘already have adult diabetes’; these are subtle differences in the metabolism of young people who are more prone to developing it later in life.
“These findings help reveal the biology of how diabetes unfolds and what features may be targetable much earlier on to prevent the onset of disease and its complications.
“This is important because we know the harmful effects of blood glucose, such as on heart disease, are not exclusive to people with diagnosed diabetes, but extend to a smaller degree to much of the population”.
Reference: Yahoo News Alexandra Thompson 14 hrs ago 20th June 2020
- Nine things you must consider before adopting a child
- An Overview of Psoriasis in Children
- DIY Fertility Tests Are On The Rise, But How Reliable Are They?
- Dentist shares when children should stop using dummies - or risk bite issues
- Top 10 benefits of breastfeeding
- Reye's syndrome: The illness that affects children
- Diphtheria symptoms: Everything you need to know after case confirmed at UK school
- Children with 'prominent' forehead may in fact be suffering from a dangerous illness
- Study assesses links between early negative life events, orbitofrontal cortical thickness and depression in young adults
- Placenta tumour: My miracle baby gave me cancer
- 7 things to look out for when it comes to vaginal health, according to gynaecologists
- What is the vaginal microbiome?
- What every woman should know about hormones, the pill and cancer
- Doctors sound alarm over new infant fentanyl syndrome
- How to boost your child’s memory
- How to Teach Deaf Children to Read
- Speaking to babies in sing-song speech ‘helps them learn language’
- Enzyme therapy approved for rare genetic condition in babies
- Paris Hilton opens up about decision to have children via surrogate
- Urgent, gentle care: life on a neonatal unit
- Woman, 70, 'gives birth to twins after IVF treatment': Ugandan becomes the oldest person to give birth in Africa, hospital says
- Scarlet fever symptoms: What parents should look out for as UK cases surge by 70 per cent
- Vaccine to tackle bronchiolitis to be offered to children next year
- What is baby-led weaning?
- What are the symptoms of tonsillitis and how is it treated?
- Home
- Aches and Pains
- Children - Insomnia
- New Born Babies
- Babies From 2-12 months
- Spina Bifida
- Equipment Used
- Drug Abuse
- Other Ingredients
- The Handicapped Child
- Videos
- BALANITIS - Aromachildhood
- Worms
- Corona virus and pregnancy
- Contact Us
- Essential Oils for General Purposes
- The Methods - Aromatherapy - Children-2
- Hydrolats, Essential Oil Waters, and infused Oils
- Ringworm
- The Methods - Aromatherapy - Children- 3
- Basic Care Kit - Children - Essential Oils
- Web Links
- Acne
- Adolescent Acne
- The A - Z of Conditions
- Arthritis (juvenile Rheumatoid)
- Herbal Healing Infused Oils
- The Cave Man Eating Plan
- Things To Make For Your First Aid Cabinet
- The Basic Care Kit For Children
- Verrucas and Warts
- Caring Touch Massage
- The Methods - Aromatherapy - Children
- The Methods - Aromatherapy - Children - 4
- Athlete's Foot - 2
We have 350 guests and no members online